Cyclic Nucleotides Biochemistry (Springer Series in Optical Sciences) by J. A. Nathanson

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Number of Pages577
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Open LibraryOL7442937M
ISBN 10038710786X
ISBN 109780387107868

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The first section focuses on the detailed pharmacology and chemistry of cyclic nucleotides, including their formation, degradation, Cyclic Nucleotides book, and interaction with various modulatory agents, such as receptors and : Paperback. About this book Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists.

Cyclic Nucleotides: Part II: Physiology and Pharmacology (Handbook of Experimental Pharmacology): Medicine & Health Science Books @ About this book The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology on the nature and role of these important chemical regulators.

This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation. The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides.

The Role of Cyclic Nucleotides in the Control of Anterior Pituitary Gland Activity F. Labrie, P. Borgeat, J. Drouin, L. Lagace, V. Giguere, V. Raymond et al. Pages Their Hormones and cyclic nucleotides, pt. C; Methods in enzymology, v. Edition/Format: Print book: EnglishView all editions and formats: Rating: (not yet rated) 0 with reviews - Be the first.

Subjects: Cyclic nucleotides. Nucleotides, Cyclic. More like this: Similar Items. Cyclic nucleotides. Berlin ; New York: Springer-Verlag, (OCoLC) Online version: Cyclic nucleotides. Berlin ; New York: Springer-Verlag, (OCoLC) Document Type: Book: All Authors / Contributors: M M Appleman; J A Nathanson; J W Kebabian.

Cyclic nucleotides exert their physiological effects by binding to four major classes of cellular receptors: cAMP- and cGMP-dependent protein kinases [1, 2], cyclic GMP-regulated phosphodiesterases [3], cAMP-binding guanine nucleotide exchange factors [4], and cyclic nucleotide-regulated cation channels.

Cyclic nucleotide-regulated cation channels are unique among these receptors because. Fourth, nucleotides are essential components of signal-transduction pathways. Cyclic nucleotides such as cyclic AMP and cyclic GMP are second messengers that transmit signals both within and between cells.

ATP acts as the donor of phosphoryl groups transferred by protein kinases. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of Cyclic Nucleotides book homeostasis and presents lectures given in the symposium.

The role of cyclic nucleotides in the regulation of muscular tissue functions and the Cyclic Nucleotides book of cyclic AMP and cyclic GMP are also looked Edition: 1. Cyclic Nucleotide Signaling - CRC Press Book Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research.

The majority of the chapters are protocol oriented, with the goal of. The role of the cyclic dinucleotide cGAMP in the immune system will covered, too. Lastly, the book will present important methodological aspects ranging from mass-spectrometric methods for cyclic nucleotide detection to the synthesis of nucleotide analogs as experimental tools and holistic methods for analysis of cyclic nucleotide effects.

Cyclic Nucleotides. (Book Reviews: Cyclic AMP, Cell Growth, and the Immune Response. Proceedings of a symposium, Marco, Island, Fla., Jan. The first chapter, "Cyclic AMP and the Immune Response," by Parker eta!, summarizes about references into 63 pages.

The abundant literature, nearly all of which has been published during the last five years, suggests that the cyclic nucleotides work both ways in the immune system, i.e., cyclic AMP is stimulatory for lymphocyte transformation.

texts All Books All Texts latest This Just In Smithsonian Libraries FEDLINK (US) Genealogy Lincoln Collection. National Emergency Library. Top Cyclic nucleotides, phosphorylated proteins, and neuronal function by Greengard, Paul, Publication date TopicsPages: Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research.

The majority of the chapters are protocol oriented, with the goal of providing clear directions for. Cyclic Nucleotide Analysis Biological Significance of Cyclic Nucleotides The second messengers adenosine 3’, 5’-cyclic monophosphate (cyclic AMP; cAMP) and guanosine 3’, 5’-cyclic monophosphate (cyclic GMP; cGMP) are important intracellular regulators downstream from GPCRs.

The second part of the book covers the roles played by cyclic nucleotides in various cell types or organs, ranging from relatively well-defined systems such as heart to poorly understood systems.

The cyclic purine nucleotides 3',5'-cAMP and 3',5'-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume ). In addition to 3',5'-cAMP and 3',5'-cGMP, so-called non-canonical cyclic nucleotides exist.

These comprise the cyclic pyrimidine nucleotides 3',5'-cCMP and 3',5'-cUMP, the purine nucleotide 3',5. CYCLIC NUCLEOTIDES AND THERAPEUTIC PERSPECTIVES By G.

Cehoitic G. Robison, pp, Pergamon Press, New York, N Y, $ The evolution of our understanding of nonneurotransmitter chemical mediators, particularly cyclic nucleotides, in neuromuscular transmission is proceeding apace. Adenosine cyclic monophosphate (cAMP) Cyclic Nucleotides • Cyclic nucleotides are formed when one phosphate group has two phosphoester connections to the same nucleoside monosaccharide.

•In most cases, they function as effectors for allosteric enzymes to regulate biological processes. Pages in category "Cyclic nucleotides" The following 7 pages are in this category, out of 7 total.

This list may not reflect recent changes (). Cyclic nucleotides and therapeutic perspectives. By G. Cehovic and G. Robison, pp, Pergamon Press, New York, NY, $Author: Benjamin R. Brooks. The cyclic nucleotides, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), have long been recognized as important intracellular signal transduction molecules, acting as second messengers between an extracellular signal such as a hormone, neurotransmitter, or cytokine and the elicited intracellular by: This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy.

Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into.

Read "Non-canonical Cyclic Nucleotides" by available from Rakuten Kobo. The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second Brand: Springer International Publishing. Purchase Hormone Action, Part C: Cyclic Nucleotides, Volume 38 - 1st Edition. Print Book & E-Book. ISBNCyclic nucleotides are important second messenger molecules in signal transduction.

Cyclic AMP (cAMP) particularly activates protein kinases that are involved in numerous signal transduction and metabolic pathways. Cyclic GMP (cGMP) mainly activates the cGMP-dependent protein kinase G and is involved in physiological processes such as eye. Find many great new & used options and get the best deals for Cyclic Nucleotides: Part I: Biochemistry by Nathanson, J.

at the best online prices at eBay. Free shipping for many products. nucleotides in whose molecules the phosphoric-acid residue, bonded to the ribose carbon atoms in the 5’ and 3’ positions, forms a ring (seeNUCLEOTIDES); universal regulators of biochemical processes in living 3’,5’-adenosine monophosphate (cyclic AMP), a white powder that is readily soluble in water, is the best studied cyclic nucleotide.

The cyclic purine nucleotides 3',5'-cAMP and 3',5'-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume ). In addition to 3',5'-cAMP and 3',5'-cGMP, so-called non-canonical cyclic nucleotides exist.

(Book Reviews: Advances in Cyclic Nucleotide Research. Vol. 1, Physiology and Pharmacology of Cyclic AMP; Advances in Cyclic Nucleotide Research. Vol. 2, New Assay Methods for Cyclic Nucleotides). Open Library is an open, editable library catalog, building towards a web page for every book ever published.

The Role of Cyclic Nucleotides in Central Synaptic Function / Renal Transport of Amino Acids by Floyd E. Bloom; 1 edition. The cyclic nucleotides, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) play an important role in the regulation of airway smooth muscle tone and activation of inflammatory cells.

Intracellular concentrations of these nucleotides are tightly regulated by phosphodiesterases (PDEs). Several families of PDEs are now recognized and, within each Cited by: Cyclic nucleotide signaling takes place in nanodomains and the A-kinase anchor proteins (AKAPS) are essential for the compartmentalized assembly of signaling proteins into functional complexes.

Reviews on the role of AKAP proteins in the physiology and pathophysiology of the heart are also included in this book. Cyclic nucleotides. The cyclic nucleotides monophosphates (cNMP) and in particular adenosine 3’,5’-cyclic monophosphate (cAMP) and guanosine 3’,5’-cyclic monophosphate (cGMP) are cyclic catalytic products of adenosine 5'-triphosphate (ATP) and guanosine 5’-triphosphate (GTP) respectively.

The impact of cyclic nucleotides such as cAMP or cGMP on normal and cancer cell growth has long been recognized. However, downstream signaling pathways that are either activated or suppressed by cyclic nucleotides that mediate growth regulation or are essential for growth have not been well defined.

The computations show that in an aqueous environment 2′,3′ cyclic nucleotides are more stable than their 3′,5′ counterparts at all temperatures up to the boiling point. In contrast, in formamide higher temperatures favor the accumulation of the 3′,5′ cyclic form, whereas below about K the 2′,3′ cyclic form becomes more stable.

Cyclic Nucleotides Cyclic AMP (cAMP) Some of the hormones that achieve their effects through cAMP as a second messenger: adrenaline; glucagon; luteinizing hormone (LH) Cyclic AMP is synthesized from ATP by the action of the enzyme adenylyl cyclase.

Binding of the hormone to its receptor activates a G protein which, in turn, activates adenylyl. Nucleotides, Cyclic > physiology > Laboratory Manuals. Plant Cells > physiology > Laboratory Manuals. Signal Transduction > physiology > Laboratory Manuals. Cyclic nucleotides > Laboratory manuals.

Plant cellular signal transduction > Laboratory manuals.cyclic nucleotide: a nucleoside monophosphate in which the phosphoryl group is linked twice to the sugar moiety; for example, adenosine 3',5'-cyclic monophosphate (cAMP).A brief treatment of nucleotides follows.

For full treatment, see nucleic acids. In the two families of nucleic acids, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA), the sequence of nucleotides in the DNA or RNA codes for the structure of proteins synthesized in the cell.

The nucleotide adenosine triphosphate (ATP) supplies the driving force of many metabolic processes.

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